Clinical Trial: International Observational Study of Intranasal 15-Gene AAV9-PHP.eB Therapy for Children With Chronic Hypoxic-Ischemic Encephalopathy (Cerebral Palsy)

U.S., Dec. 5 -- ClinicalTrials.gov registry received information related to the study (NCT07264166) titled 'International Observational Study of Intranasal 15-Gene AAV9-PHP.eB Therapy for Children With Chronic Hypoxic-Ischemic Encephalopathy (Cerebral Palsy)' on Nov. 24.

Brief Summary: This international study, organized by Healing Hope International, is an observational registry designed to collect real-world data on children living with chronic hypoxic-ischemic encephalopathy (HIE) who receive an emerging intranasal gene therapy based on the AAV9-PHP.eB viral vector.

The investigational therapy delivers a panel of 15 restorative genes that support brain repair, reduce inflammation, promote myelination, and improve neural communication. ...