U.S., Dec. 6 -- ClinicalTrials.gov registry received information related to the study (NCT07265895) titled 'Inherited Retinal Diseases: Natural History and Genotype-Phenotype Correlations' on Nov. 18.
Brief Summary: Inherited Retinal Diseases (IRDs) are a heterogeneous group of genetically based degenerative retinal disorders, representing a major cause of visual impairment and blindness in working-age adults. Despite the approval of the first gene therapy for RPE65-related IRD (voretigene neparvovec) in 2017, most IRDs remain untreatable, though many gene therapies are in development. Effective trial design and therapy development require a deep understanding of disease natural history and genotype-phenotype correlations. Over 270 IRD-ass...