U.S., Dec. 19 -- ClinicalTrials.gov registry received information related to the study (NCT07292363) titled 'Inflammation-Related Endothelial Barrier Dysfunction in Patients With Apical Periodontitis' on Dec. 05.
Brief Summary: Inflammation is a common factor in chronic periodontitis and systemic diseases. However, to date, there is no scientific evidence supporting a causal effect of inflammation caused by apical periodontitis on endothelial barrier dysfunction.
A case-control study was designed to evaluate serum levels of endothelial barrier dysfunction factors in a sample of healthy patients aged 25 to 55, with or without apical periodontitis, before endodontic treatment and 6 and 12 months after treatment.
The aim of the study is to ...