U.S., Jan. 9 -- ClinicalTrials.gov registry received information related to the study (NCT07325747) titled 'Immediate Versus Delayed Surgical Reconstruction of Peri-implantitis Intra-bony Defects.' on Dec. 10, 2025.

Brief Summary: The purpose of this study is to test the comparative efficacy of two surgical approaches (immediate versus delayed GBR) for the surgical reconstruction of peri-implantitis intra-bony defects in terms of the clinical, radiographical, histological, volumetric, microbiological, and patient-reported outcomes.

The investigators hypothesize that in certain clinical situations, treatment of peri-implantitis intra-bony defects with the use of a compound bone grafting material (mixture of allogenic bone substitutes) and ...