U.S., June 14 -- ClinicalTrials.gov registry received information related to the study (NCT07019142) titled 'High-fat Diet (HFD) and Small Intestinal Microbiome' on Oct. 16, 2020.
Brief Summary: The investigators aim to characterize the upper small intestinal microbiome in healthy conditions in dependency on feeding condition (starved vs. high-fat-challenged) and diet (before and after 3 day high-fat-diet)
Primary outcome will be the maximum culturable bacteria (aerobic and anaerobic) in small intestinal luminal content during acute liquid-fat challenge before vs. after a short-term (3 day) high-fat-diet
In this pilot study, healthy volunteers will undergo i) an upper endoscopy for harvesting of small intestinal juice, mucosal biopsies a...