U.S., Jan. 8 -- ClinicalTrials.gov registry received information related to the study (NCT07322055) titled 'Genetic and Clinical Correlates of Disruptive Behavior Disorder With and Without Callous-Unemotional Traits' on Dec. 22, 2025.
Brief Summary: Disruptive Behavior Disorders (DBD), such as Conduct Disorder (CD) and Oppositional Defiant Disorder (ODD), affect children and adolescents in different ways. Research has shown that some individuals with DBD also display callous-unemotional (CU) traits, including a lack of guilt, uncaring behavior, and shallow emotions. This subgroup tends to have more severe symptoms and a higher risk of negative outcomes.
Previous studies suggest that genetic factors may play a role in the development of DB...