U.S., July 25 -- ClinicalTrials.gov registry received information related to the study (NCT07083882) titled 'Faecal Autologous Capsule Transplantation for Type 1 Diabetes Mellitus' on July 11.
Brief Summary: SUMMARY
Rationale:
The(small) intestinal microbiota composition has been implicated to play an important role in (human) metabolism, as well as autoimmune diseases such as type 1 diabetes mellitus. Faecal microbiota transplantation (FMT) has been shown to significantly alter the microbiota composition, without any serious side-effects. It was recently demonstrated that multiple infusions of own faeces(autologous) preserved residual beta cell function up to one year after start of the FMT. In a proof-of-principle study it was found th...