U.S., Dec. 30 -- ClinicalTrials.gov registry received information related to the study (NCT07308470) titled 'Etodolac Nanogel as an Adjunct to Physiotherapy for Knee Osteoarthritis' on Dec. 07.

Brief Summary: Brief Summary:

Knee osteoarthritis (OA) is a common, disabling condition affecting the weight-bearing knee joint, leading to pain, reduced function, and muscle weakness, particularly of the quadriceps. Strengthening exercises are recommended to improve joint stability, physical function, and slow disease progression. Etodolac, a selective NSAID approved for osteoarthritis, has proven analgesic and anti-inflammatory effects. This study investigates the adjunctive effect of a topical Etodolac-loaded solid lipid nanoparticle gel combine...