U.S., April 17 -- ClinicalTrials.gov registry received information related to the study (NCT06929416) titled 'Estrogen and Propofol Injection Pain: An Observational Study' on April 08.
Brief Summary: This prospective observational study aims to investigate the relationship between serum estrogen concentration and the incidence and severity of propofol injection pain (PIP) in female patients undergoing general anesthesia. The study will include 90 ASA I-II female patients aged 18-45. One group will consist of IVF patients with supraphysiological estrogen levels, while the control group will include patients with normal estrogen levels undergoing other elective procedures. Pain will be assessed using a standardized four-point behavioral pain...