U.S., Feb. 15 -- ClinicalTrials.gov registry received information related to the study (NCT06827470) titled 'Establishing a Controlled Human Infection Model of Pertactin-deficient Bordetella Pertussis' on Jan. 14.
Brief Summary: The overall goal of this study is to establish a PRN-deficient pertussis Controlled Human Infection Model (CHIM) that represents currently circulating isolates, in the context of a North American exposure (vaccination and infection) pedigree.
Study Start Date: April 01
Study Type: INTERVENTIONAL
Condition:
Pertussis (whooping Cough)
Intervention:
BIOLOGICAL: Biological: Bordetella pertussis J820
Intranasal inoculation of Bordetella pertussis J820 in each naris on Day 1 of the study.
Recruitment Status: NOT_...