U.S., Feb. 12 -- ClinicalTrials.gov registry received information related to the study (NCT07404085) titled 'Epigenetic Enhancement of Cognitive Training in Aging Mood Disorder Populations' on Dec. 11, 2025.
Brief Summary: The aim of this clinical trial is to investigate the effects of a three-week virtual reality-based cognitive remediation training (VR-CRT) programme in combination with daily intake of a histone deacetylase inhibitor (HDACi) sodium butyrate on cognition in symptomatically stable patients with mood disorders (depression or bipolar disorder).
The investigators hypothesize that the VR-based cognitive remediation training (VR-CRT) combined with HDACi butyrate vs. a VR-based control treatment combined with placebo will impro...