U.S., Sept. 17 -- ClinicalTrials.gov registry received information related to the study (NCT07176221) titled 'Endoscopic Cardial Constriction Ligation (ECCL) for Refractory GERD Using a Disposable Endoscope' on Aug. 16.

Brief Summary: This study will recruit patients aged 18-80 with refractory gastroesophageal reflux disease (GERD). These patients had a disease course of more than six months, experienced typical symptoms such as acid reflux and heartburn, and had no symptom relief after taking a double dose of acid-suppressing medication for eight consecutive weeks. All eligible participants will undergo Endoscopic Cardial Constriction Ligation (ECCL) using a disposable endoscope. The procedure will follow a standardized protocol: mucosal ...