U.S., Jan. 13 -- ClinicalTrials.gov registry received information related to the study (NCT07331935) titled 'Efficacy of Topical Coenzyme Q10 and Curcumin for Oral Leukoplakia Treatment' on Dec. 27, 2025.
Brief Summary: Oral leukoplakia (OL) is recognized as the most common potentially malignant disorder of the oral mucosa. The pathogenesis of OL is complex and multifactorial, with oxidative stress playing a central role. Topical antioxidants have gained attention as therapeutic options to help stabilize lesions and potentially prevent malignant transformation. Both CoQ10 and curcumin have demonstrated a clinical success as strong antioxidants showing their capacity to reduce the lesion size and to stabilize the disease, ultimately prevent...