U.S., Jan. 23 -- ClinicalTrials.gov registry received information related to the study (NCT07357337) titled 'Efficacy of Oral Metformin vs Oral Doxycycline in Treating Acne Vulgaris' on Jan. 06.

Brief Summary: The goal of the clinical trial is to learn if oral metformin works to treat moderate to severe acne vulgaris.

Investigators will compare this drug to oral doxycycline to see if this drug works to treat acne. All participants will be divided into two groups.

Group A will be given oral Metformin 500 mg to be taken twice daily, while Group B patients will be given oral Doxycycline 100 mg once daily. They will be assessed by the scoring method Total Lesion Count (TLC) and the Global Acne Grading System (GAGS) at each follow-up (i.e., a...