Clinical Trial: Efficacy and Safety of MSLN CAR-T in Advanced Malignant Tumors

U.S., Feb. 11 -- ClinicalTrials.gov registry received information related to the study (NCT07399769) titled 'Efficacy and Safety of MSLN CAR-T in Advanced Malignant Tumors' on Feb. 03.

Brief Summary: 1. Study Title:

Efficacy and safety of MSLN CAR-T in advanced malignant tumors

2. Study Objectives:

Primary: To evaluate the safety and tolerability of MSLN-targeted CAR-T cell therapy in patients with stage III/IV advanced malignant tumors.

Secondary: To preliminarily evaluate the efficacy of MSLN-targeted CAR-T cell therapy in this patient population.

Exploratory: To assess in vivo expansion and persistence of infused MSLN-targeted CAR-T cells and explore correlations with clinical outcomes.

3. Participant Intervention:

Participants w...