U.S., Feb. 12 -- ClinicalTrials.gov registry received information related to the study (NCT07404319) titled 'Effectiveness of Exercise Alone and tDCS+Exercise on Cognitive Function Improvement in Patients With Treatment Resistant Schizophrenia' on Feb. 04.
Brief Summary: Cognitive impairment is a major determinant of disability in schizophrenia. Aerobic exercise improves global cognition in schizophrenia, particularly working memory and attention/vigilance. Transcranial direct current stimulation (tDCS) targeting frontal regions has shown promise for cognitive deficits, including working memory improvements in some studies. This randomized 2x2 factorial trial will test the independent and combined effects of supervised aerobic exercise and...