U.S., July 25 -- ClinicalTrials.gov registry received information related to the study (NCT07082569) titled 'Effect of Ventilation Mode in the Pupillary Light Reflex: A Crossover Study' on July 05.
Brief Summary: The goal of this clinical trial is to explore whether different modes of mechanical ventilation affect pupillary constriction velocities in critically ill patients without brain injury. The study aims to determine whether the type of mechanical ventilation (volume control, pressure control, or pressure-regulated volume control) influences the maximum and mean constriction velocity measured by automated pupillometry. The trial also investigates whether changes in pupil dynamics reflect subtle alterations in brainstem-autonomic inte...