U.S., Dec. 4 -- ClinicalTrials.gov registry received information related to the study (NCT07262242) titled 'Effect of Opioid-sparing Anesthesia on Quality of Recovery After Emergency Laparotomy' on Nov. 17.
Brief Summary: Opioids are widely used during anesthesia for pain control, but they cause many side effects-such as nausea, constipation, respiratory depression, dependence, and delayed recovery. They can also worsen low blood pressure in patients with unstable circulation. Because of these risks, multimodal analgesia is recommended to reduce opioid use.
Research on other non-opioid options is limited. Systemic lidocaine offers anti-inflammatory and opioid-sparing benefits and improves recovery in elective colorectal surgery, but its r...