U.S., June 6 -- ClinicalTrials.gov registry received information related to the study (NCT07006675) titled 'Effect of NSAIDs on Union, Opioid Utilization and Pain Management for Tibia Fractures: A Pragmatic, Randomized Controlled Trial' on May 27.

Brief Summary: Two arm, pragmatic, randomized controlled multicenter Phase III noninferiority trial evaluating the efficacy of standard pain management without NSAIDs (Group 1) vs. standard pain management plus up to 6 weeks of NSAIDs (Group 2) in the treatment of tibial shaft fractures.

Study Start Date: May 26, 2021

Study Type: INTERVENTIONAL

Condition: Tibial Fractures Pain

Intervention: DRUG: 600 mg Ibuprofen

Treatment patients will receive oral ibuprofen 600 mg three times a day (tid)...