U.S., Sept. 10 -- ClinicalTrials.gov registry received information related to the study (NCT07161973) titled 'Effect of Dietary Nitrate on Immobilization-induced Changes in Skeletal Muscle in Young Healthy Men' on Aug. 08.
Brief Summary: Diminished use of skeletal muscle, such as occurs with many chronic diseases (e.g., heart failure or cancer cachexia), denervation, bedrest, immobilization (e.g., limb casting or bracing), etc., is a common clinical condition affecting untold millions of individuals each year. Such disuse leads to a rapid decline in muscle fiber area and hence whole muscle size, contributing to a decrease in strength, speed, and power as well as alterations in energy metabolism. Collectively, these changes lead to reduced ...