U.S., Jan. 24 -- ClinicalTrials.gov registry received information related to the study (NCT07362966) titled 'Effect of Colchicine on Progression of Coronary Atherosclerosis in Patients With TET2-CHIP Variant' on Jan. 15.
Brief Summary: This study aims to investigate whether TET2-associated clonal hematopoiesis of indeterminate potential (TET2-CHIP) can serve as a biomarker to guide precision use of colchicine in a population of clinically stable post-ACS patients receiving standard of care (SoC) therapy. Specifically, we will evaluate whether TET2-CHIP status predicts a differential response to colchicine. As a pilot study, it also aims to provide detailed data supporting design of further trial, such as sample size calculating, endpoint o...