U.S., Dec. 20 -- ClinicalTrials.gov registry received information related to the study (NCT07295314) titled 'Effect of Antifungals on the Intestinal Microbiome - a Randomized, Controlled, Proof-of-concept Trial' on Dec. 08.
Brief Summary: The goal of this clinical trial is to learn how the antifungal drug fluconazole affects the gut microbiome and immune system in healthy volunteers.
The main questions it aims to answer are:
* Does fluconazole change the gut bacteriome and mycobiome composition after 14 days of treatment?
* How long do these changes last (4 weeks and 6 months after treatment)?
* Does fluconazole affect the body's immune responses, such as blood cell activity and antifungal antibodies?
Researchers will compare two grou...