U.S., July 26 -- ClinicalTrials.gov registry received information related to the study (NCT07085624) titled 'Early Optimization of Ceftazidime Regimen in Critical Care' on March 25.
Brief Summary: Hospital-acquired infections, most of which are caused by Gram-negative bacteria, are common in intensive care units and have a major impact on patient prognosis. Patient survival in severe sepsis and septic shock depends on the early administration of appropriate antibiotic therapy, with mortality increasing by 7.6% for each hour of delay, justifying the probabilistic use of broad-spectrum antibiotics such as ceftazidime, an essential betalactamine, particularly used for its activity against Pseudomonas aeruginosa, a frequent pathogen in nosocom...