U.S., Jan. 28 -- ClinicalTrials.gov registry received information related to the study (NCT07370753) titled 'Early Continuous Renal Replacement Therapy for Pediatric Septic Shock' on Jan. 01.
Brief Summary: Septic shock is a major cause of morbidity and mortality in critically ill children. Continuous renal replacement therapy (CRRT) is increasingly used as adjunctive support in pediatric septic shock to improve hemodynamic stability, modulate inflammatory responses, and correct metabolic disturbances. However, evidence regarding optimal indications, timing, and clinical outcomes of early CRRT use in children remains limited.
This prospective observational study aims to evaluate associations between early CRRT use and changes in hemodynam...