U.S., Dec. 6 -- ClinicalTrials.gov registry received information related to the study (NCT07267559) titled 'Dual Orexin Antagonism and Emotion and Affective Processing Study' on Nov. 14.
Brief Summary: In this study, the investigators will examine the effects of blocking the orexin system on human behaviour and brain function using daridorexant, a medication that inhibits orexin activity. Orexin is a brain chemical involved in regulating sleep, emotion, motivation, and stress responses, which are often disrupted in mental health disorders. Healthy volunteers will be randomly assigned to receive a single dose of daridorexant or placebo in a double-blind design. Participants will then complete behavioural and cognitive tasks assessing emotio...