U.S., Jan. 31 -- ClinicalTrials.gov registry received information related to the study (NCT06801873) titled 'Determining the Fingerprint of Endotoxin Tolerance' on Jan. 10.
Brief Summary: An explorative, prospective study in 100 healthy volunteers who will be challenged with endotoxin twice to identify SNPs and transcripts that are associated with the degree of endotoxin tolerance
Study Start Date: May 27, 2019
Study Type: INTERVENTIONAL
Condition:
Endotoxemia
Sepsis
Systemic Inflammation
Immunosuppresion
Intervention:
OTHER: Endotoxin (E. coli O:113, Reference Endotoxin)
Intravenous administration of 2 ng/kg endotoxin. This is a non-investigational product. Endotoxin is used as challenge agent to achieve a controlled inflammatory s...