U.S., Feb. 8 -- ClinicalTrials.gov registry received information related to the study (NCT06813664) titled 'ctDNA-Guided CURB for OPD mNSCLC on TKI (CURB-TKI)' on Jan. 24.
Brief Summary: This is an open-label, prospective single arm Phase II trial that investigates the role of ablative stereotactic body radiation therapy (SBRT) in oncogene driven metastatic non-small cell lung cancer (mNSCLC) patients with oligoprogressive disease (OPD) on targeted therapy (TKI) followed by circulating tumor DNA (ctDNA) analysis for tailoring targeted therapies.
Study Start Date: April 01
Study Type: INTERVENTIONAL
Condition:
Metastatic NSCLC - Non-Small Cell Lung Cancer
OligoProgressive Metastatic Disease
Intervention:
RADIATION: Radiotherapy
SBRT/...