Clinical Trial: Consolidative Use of Radiotherapy to Block Oligoprogression in Patients With Metastatic Melanoma

U.S., Aug. 9 -- ClinicalTrials.gov registry received information related to the study (NCT07112170) titled 'Consolidative Use of Radiotherapy to Block Oligoprogression in Patients With Metastatic Melanoma' on July 29.

Brief Summary: This open-label, prospective, single-arm Phase II trial explores whether adding stereotactic body radiotherapy (SBRT) or hypofractionated radiotherapy to oligoprogressive lesions can help delay disease progression in patients with metastatic melanoma. Participants may have up to ten extracranial oligoprogressive sites, with no upper limit on the total number of metastatic lesions. The study aims to assess whether targeting these progressing sites with focused radiotherapy can extend progression-free survival in...