U.S., Dec. 3 -- ClinicalTrials.gov registry received information related to the study (NCT07258628) titled 'Comparison of Fentanyl and Magnesium to Control Reflex Hemodynamics in Patients Aged 50 and Older' on Sept. 19.
Brief Summary: This prospective, randomized, controlled trial aims to evaluate the effects of magnesium sulfate and fentanyl on the hemodynamic response to endotracheal intubation in surgical patients aged 50 years and older. A total of 75 patients will be enrolled and randomized into three groups: magnesium sulfate alone, magnesium sulfate plus fentanyl, and fentanyl alone. The primary outcome measures are changes in mean arterial pressure (MAP) and heart rate before and after intubation. Secondary outcomes include BIS, SE...