U.S., June 6 -- ClinicalTrials.gov registry received information related to the study (NCT07007221) titled 'Clinical Trials to Evaluate Metformin to Treat Depression in People Living With HIV' on March 12.
Brief Summary: Depression in HIV occurs commonly and causes poor HIV outcomes with public health implications.
Depression prevalence in HIV-infected persons is estimated at 26% compared to 5% in the general population. Adherence to antiretroviral medication is a life-saving treatment in HIV, but depression can reduce engagement in care and adherence to medication. Depression is also associated with poorer levels of viral suppression and even mortality. Overall, those with depression and HIV are less likely to return to health and remain...