U.S., March 25 -- ClinicalTrials.gov registry received information related to the study (NCT06892145) titled 'Clinical Trial of CD19 Targeted CAR-T Cell in Refractory Adult SLE' on March 18.
Brief Summary: This is a single-arm, open, dose-increasing and dose-expanding phase I clinical trial to investigate the safety, tolerability and cytodynamic characteristics of MC-1-50 cell preparation, and to preliminatively observe the efficacy of MC-1-50 cell preparation in patients with refractory SLE, and to explore the applicable dose regimen for phase II clinical trials.
Study Start Date: April 02
Study Type: INTERVENTIONAL
Condition:
Systemic Lupus Erythematosus (SLE)
Refractory
Intervention:
BIOLOGICAL: MC-1-50
A single infusion of CD19 ...