U.S., Jan. 27 -- ClinicalTrials.gov registry received information related to the study (NCT07366905) titled 'Clinical Observation of Bupivacaine Liposome for Lower Extremity Nerve Block' on Jan. 08.
Brief Summary: This prospective, sequential dose-finding clinical observational study aims to estimate the median effective concentration (EC50) and the 95% effective concentration (EC95) of liposomal bupivacaine for ultrasound-guided femoral nerve block. Sensory and motor block endpoints are evaluated separately at 30 minutes after block placement using a modified up-and-down (sequential allocation) design, with trial termination after eight reversal points.
Study Start Date: Feb., 2026
Study Type: INTERVENTIONAL
Condition:
Patients Eligib...