U.S., April 30 -- ClinicalTrials.gov registry received information related to the study (NCT06949176) titled 'Clinical Investigation of Chemomechanical Parameters for an Efficient Disinfection of the Root Canal' on April 01.

Brief Summary: The aim of the study is first, to evaluate the clinical antibacterial efficacy of two different NaOCl concentrations (2,5% and 5%) under a predefined irrigant flow rate in teeth with pulp necrosis and apical periodontitis by using Real-time PCR. . Second, to evaluate the efficacy of final irrigation by assessing, if possible, a numerical definition for that "so called" as "copious irrigation".

Besides the total microbial load, the antibacterial efficacy of final irrigation procedure against two differen...