U.S., Jan. 15 -- ClinicalTrials.gov registry received information related to the study (NCT07341412) titled 'Clinical and Genetic Aspects in Fetuses and Children With Sex Chromosome Disorders' on Dec. 12, 2025.
Brief Summary: The aim of the project is to:
1. Investigate organ development and growth in fetuses with sex chromosome disorders;
2. Investigate growth, development, and morbidity in children with sex chromosome disorders during the first years of life;
3. Delineate how variations in sex chromosome number affect the epigenetic and genetic mechanisms regulating gene expression in the placenta and in multiple tissues of the child after birth over time during early childhood;
4. Investigate the gut microbiome in children with sex ...