U.S., Dec. 24 -- ClinicalTrials.gov registry received information related to the study (NCT07298707) titled 'Cervical Cytology DNA Methylation for Endometrial Lesion Screening and Follow-up' on Dec. 09.

Brief Summary: The goal of this observational study is to evaluate the accuracy of a novel molecular test for screening and monitoring endometrial lesions in women at medium-to-high risk for endometrial cancer.

The main questions it aims to answer are:

* What is the sensitivity and specificity of the CISENDO test (a DNA methylation test on cervical cytology samples) for detecting histologically confirmed endometrial intraepithelial neoplasia (EIN) or invasive endometrial cancer?

* How do DNA methylation levels change during the follow-up...