U.S., Aug. 16 -- ClinicalTrials.gov registry received information related to the study (NCT07125781) titled 'Central Sensitization and Nociplastic Pain in Pes Planus' on Aug. 10.
Brief Summary: Background:
Pes planus, commonly known as flatfoot, is a condition characterized by the collapse of the medial longitudinal arch of the foot. While some individuals remain asymptomatic, many experience foot or leg pain, walking difficulties, and functional limitations. In some cases, symptoms persist despite adequate conventional treatment. This suggests that central pain mechanisms, such as central sensitization and nociplastic pain, may contribute to ongoing symptoms. These mechanisms involve changes in the central nervous system that amplify pai...