Clinical Trial: Cell-free DNA Analysis of Spent Embryo Culture Media as a Non-invasive Approach for Preimplantation Genetic Diagnosis

U.S., July 23 -- ClinicalTrials.gov registry received information related to the study (NCT07076719) titled 'Cell-free DNA Analysis of Spent Embryo Culture Media as a Non-invasive Approach for Preimplantation Genetic Diagnosis' on July 12.

Brief Summary: This study aims to evaluate the feasibility and accuracy of using cfDNA analysis of spent embryo culture media as a non-invasive approach for PGD. Specifically, the objectives of the study are:

1. To collect SCM from blastocysts of good quality obtained from IVF cycles.

2. To extract cfDNA from the collected SCM using a commercially available kit.

3. To assess the chromosomal content in both cfDNA and gDNA samples via array-based comparative genomic hybridization (aCGH).

4. To compare ...