U.S., Nov. 26 -- ClinicalTrials.gov registry received information related to the study (NCT07247396) titled 'CEA CAR-T Therapy After Cytoreduction in Colorectal Cancer Patients With Peritoneal Metastases' on Nov. 17.
Brief Summary: This single-arm, open-label, dose-escalation trial aims to evaluate the safety and efficacy of CEA-targeted CAR-T cells and to obtain their pharmacokinetic profile in patients with advanced colorectal cancer and peritoneal metastases after cytoreductive surgery; the recommended dose will then be derived from these data.
Study Start Date: Nov. 03
Study Type: INTERVENTIONAL
Condition:
Peritoneal Metastases From Colorectal Cancer
Intervention:
BIOLOGICAL: CEA-targeted CAR-T cells
Administration method: intra...