U.S., Nov. 21 -- ClinicalTrials.gov registry received information related to the study (NCT07238400) titled 'Cardiac Effects of Mineralocorticoid Receptor Antagonism After Preeclampsia' on Nov. 11.

Brief Summary: The goal of this clinical trial is to determine if the medication eplerenone yields greater improvements in coronary microvascular function than chlorthalidone in women who experienced preeclampsia during pregnancy and subsequently developed chronic hypertension. The main Aims are:

* To test the hypothesis that, in women with prior preeclampsia, current chronic hypertension, and concentric LV remodeling, eplerenone improves coronary microvascular function vs. chlorthalidone.

* To test the hypothesis that, in women with prior pre...