U.S., Dec. 10 -- ClinicalTrials.gov registry received information related to the study (NCT07271589) titled 'Biological and Clinical Underpinnings of Postoperative Pain - Mastectomy' on Nov. 27.
Brief Summary: Persistent pain after mastectomy remains a significant clinical challenge that can delay recovery, reduce quality of life, and increase long-term healthcare burden. The goal of this study is to gain a deeper understanding of the biological and clinical factors that influence pain severity after mastectomy and contribute to the transition from acute to chronic postoperative pain. Guided by a biopsychosocial framework, this research will address the following aims:
1. We will use standardized experimental pain testing before surgery t...