U.S., June 27 -- ClinicalTrials.gov registry received information related to the study (NCT07039734) titled 'Assessment of Ovarian Reserve in Patients With Fragile X Premutation' on May 14.
Brief Summary: Premature ovarian failure (POF) affects 1% of women under the age of 40 and is defined by the presence of a disorder of the cycle such as spaniomenorrhea or amenorrhea and an increase in FSH > 25 IU/l on two occasions a few weeks apart.
The prevalence of premature ovarian failure in women carrying the FMR1 gene premutation is estimated to be between 13 and 26%. Conversely, patients carrying premutations have been identified in 0.8 to 7.5% of women with sporadic POI and up to 13% of women with a familial form of POI.
The variability in p...