Clinical Trial: Antibacterial Efficacy and Outcomes of Root Canal Irrigation Methods

U.S., May 7 -- ClinicalTrials.gov registry received information related to the study (NCT06959602) titled 'Antibacterial Efficacy and Outcomes of Root Canal Irrigation Methods' on April 28.

Brief Summary: This randomized clinical trial aims to evaluate the antibacterial efficacy and treatment outcomes of three different final irrigation protocols during root canal therapy: 2.5% sodium hypochlorite alone, sodium hypochlorite with Passive Ultrasonic Irrigation (PUI), and sodium hypochlorite with XP-Endo Finisher activation. Sixty-six single-rooted teeth with pulp necrosis and apical periodontitis will be randomly assigned to one of the three groups. Antibacterial efficacy will be assessed through Real-Time PCR quantification of total bacteri...