Clinical Trial: An Open-label, Phase 2 Pilot Study on the Efficacy and Safety of Piclidenoson in Patients With Lowe Syndrome

U.S., Feb. 14 -- ClinicalTrials.gov registry received information related to the study (NCT07410455) titled 'An Open-label, Phase 2 Pilot Study on the Efficacy and Safety of Piclidenoson in Patients With Lowe Syndrome' on Feb. 08.

Brief Summary: The primary objective of this trial is to:

1. Evaluate the efficacy of piclidenoson to increase renal uptake of 99mTc-labeled DMSA, in comparison to baseline, after 6 months (26 weeks) of treatment as a measure the reabsorption capacity of LMWPs by renal proximal tubules.

The secondary objectives of this trial are to:

1. Evaluate changes in urinary excretion of LMWPs and other clinical parameters of renal Fanconi syndrome

2. Evaluate safety of piclidenoson in patients with Lowe syndrome

Study ...