U.S., Aug. 28 -- ClinicalTrials.gov registry received information related to the study (NCT07143656) titled 'Amyotrophic Lateral Sclerosis: A Multicenter Retrospective Observational Registry' on Aug. 20.
Brief Summary: This retrospective observational study will analyze de-identified clinical data from patients with amyotrophic lateral sclerosis (ALS) collected at multiple centers over 7 years. The primary objective is to describe disease progression using the ALS Functional Rating Scale-Revised (ALSFRS-R). Secondary objectives include evaluating survival, ventilatory decline, and correlations between available biomarkers (e.g., neurofilament light chain, cytokines) and disease trajectory. No new interventions or patient contact will occur...