U.S., Feb. 6 -- ClinicalTrials.gov registry received information related to the study (NCT07389785) titled 'Age Related Chromatin Remodelling as a Therapeutic Target for Organ Protection in Cardiac Surgery' on Sept. 17, 2025.
Brief Summary: People who have multiple long-term conditions (MLTC) like kidney disease or lung disease are at higher risk of developing organ damage and poor quality of life following heart surgery. Decades of research have failed to identify drugs or treatments that prevent this.
Our research has shown that people with MLTC have changes in their heart cells before surgery that are referred to by researchers as Biological Ageing. These changes combine to make people with MLTC more susceptible to organ damage after h...