U.S., April 30 -- ClinicalTrials.gov registry received information related to the study (NCT06950099) titled 'Advanced Neuroimaging in Idiopathic Intracranial Hypertension' on March 24.
Brief Summary: Idiopathic intracranial hypertension (IIH) is characterized by elevated intracranial pressure leading to symptoms like papilledema, headache, and cognitive dysfunction. While the etiology is complex, abnormal cerebrospinal fluid dynamics due to venous outflow restriction from transverse sinus stenosis (TSS) is common. TSS may disrupt the glymphatic system, a brain-wide network facilitating cerebrospinal fluid and interstitial fluid exchange, by impairing CSF absorption, altering perivascular space dynamics, and disrupting pressure gradients c...