U.S., Nov. 11 -- ClinicalTrials.gov registry received information related to the study (NCT07225829) titled 'A Trial to Investigate the Safety and Efficacy of Intra-articular 4P004 Injection in Subjects With Knee Synovitis and Osteoarthritis' on Sept. 24.

Brief Summary: This phase 2a trial is an international, multicenter, randomized, double-blind, placebo-controlled trial to investigate the efficacy and safety of one single intra-articular (IA) injection of 4P004 or placebo in:

* patients between 40 and 80 years of age,

* with synovitis and grade 2 to 4 osteoarthritis (OA) of the knee according to Kellgren and Lawrence (KL) classification.

Study Start Date: June 17

Study Type: INTERVENTIONAL

Condition: Knee Osteoarthritis Synovitis ...