Clinical Trial: A Study to Evaluate the Safety of Increasing Doses of DF5112 in Healthy Adults

U.S., Nov. 19 -- ClinicalTrials.gov registry received information related to the study (NCT07232121) titled 'A Study to Evaluate the Safety of Increasing Doses of DF5112 in Healthy Adults' on Nov. 13.

Brief Summary: This is a double-blind, randomized, placebo-controlled, single ascending dose (SAD) study to evaluate safety, tolerability, pharmacokinetics (PK), immunogenicity and pharmacodynamics (PD) of DF5112 in healthy adult participants. A total of 64 participants are planned to be randomized into 8 cohorts. Additional cohorts at intermediate dose levels may be evaluated. Each cohort will include 8 healthy participants randomized to receive DF5112 or placebo through intravenous (IV) or subcutaneous (SC) administration. Following dose ad...