U.S., Nov. 29 -- ClinicalTrials.gov registry received information related to the study (NCT07254416) titled 'A Study on Nausea and Vomiting Caused by T-DXd in Breast Cancer Patients' on Nov. 19.
Brief Summary: This study was a multicenter, prospective, controlled trial involving 120 breast cancer patients receiving T-DXd-based therapy. Participants were randomly assigned to either the experimental group (NEPA plus megestrol acetate) or the control group (NEPA plus dexamethasone), with 60 patients in each group. The intervention was administered over two treatment cycles. During this period, the onset time, frequency, and severity of nausea and vomiting were recorded and subjected to statistical analysis.
The primary objective of this stud...