U.S., Dec. 20 -- ClinicalTrials.gov registry received information related to the study (NCT07294872) titled 'A Study of TIL in Advanced Solid Tumors (CZ)' on Dec. 04.
Brief Summary: This study is to investigate the safety and efficacy of tumor infiltrating lymphocyte (TIL) therapy in patients with advanced solid tumors. Autologous TILs and gene-edited TILs are expanded from tumor resections and infused i.v. into the patient after NMA lymphodepletion treatment with hydroxychloroquine(600mg,single-dose) and cyclophosphamide.
Study Start Date: Dec. 08
Study Type: INTERVENTIONAL
Condition:
Solid Tumor, Adult
Intervention:
BIOLOGICAL: GC101TIL
A tumor sample is resected from each participant and cultured ex vivo to expand the population ...